Cargando…

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

Sound stimuli elicit movement of the stereocilia that make up the hair bundle of cochlear hair cells, putting tension on the tip links connecting the stereocilia and thereby opening mechanotransducer (MT) channels. Tmc1 and Tmc2, two members of the transmembrane channel–like family, are necessary fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kyunghee X., Beurg, Maryline, Hackney, Carole M., Furness, David N., Mahendrasingam, Shanthini, Fettiplace, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813385/
https://www.ncbi.nlm.nih.gov/pubmed/24127526
http://dx.doi.org/10.1085/jgp.201311068