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Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases. Powered by the natural diversity of immune response, hpAbs are effective in treating diseases caused...

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Detalles Bibliográficos
Autores principales: Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813428/
https://www.ncbi.nlm.nih.gov/pubmed/24205120
http://dx.doi.org/10.1371/journal.pone.0078119