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Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle
Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases. Powered by the natural diversity of immune response, hpAbs are effective in treating diseases caused...
Autores principales: | Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813428/ https://www.ncbi.nlm.nih.gov/pubmed/24205120 http://dx.doi.org/10.1371/journal.pone.0078119 |
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