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N-Acetylcysteine Prevents Spatial Memory Impairment Induced by Chronic Early Postnatal Glutaric Acid and Lipopolysaccharide in Rat Pups

BACKGROUND AND AIMS: Glutaric aciduria type I (GA-I) is characterized by accumulation of glutaric acid (GA) and neurological symptoms, such as cognitive impairment. Although this disease is related to oxidative stress and inflammation, it is not known whether these processes facilitate the memory im...

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Detalles Bibliográficos
Autores principales: Rodrigues, Fernanda S., Souza, Mauren A., Magni, Danieli V., Ferreira, Ana Paula O., Mota, Bibiana C., Cardoso, Andreia M., Paim, Mariana, Xavier, Léder L., Ferreira, Juliano, Schetinger, Maria Rosa C., Da Costa, Jaderson C., Royes, Luiz Fernando F., Fighera, Michele R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813430/
https://www.ncbi.nlm.nih.gov/pubmed/24205200
http://dx.doi.org/10.1371/journal.pone.0078332