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Plasma Metabolomics Reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of the Transcription Factor 7-Like 2 Polymorphism rs7903146

AIMS/HYPOTHESIS: Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene have been shown to display a powerful association with type 2 diabetes. The aim of the present study was to evaluate metabolic alterations in carriers of a common TCF7L2 risk variant. METHODS: Seventeen non-diabetic su...

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Detalles Bibliográficos
Autores principales: Then, Cornelia, Wahl, Simone, Kirchhofer, Anna, Grallert, Harald, Krug, Susanne, Kastenmüller, Gabi, Römisch-Margl, Werner, Claussnitzer, Melina, Illig, Thomas, Heier, Margit, Meisinger, Christa, Adamski, Jerzy, Thorand, Barbara, Huth, Cornelia, Peters, Annette, Prehn, Cornelia, Heukamp, Ina, Laumen, Helmut, Lechner, Andreas, Hauner, Hans, Seissler, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813438/
https://www.ncbi.nlm.nih.gov/pubmed/24205231
http://dx.doi.org/10.1371/journal.pone.0078430