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miR-582-5p Is Upregulated in Patients with Active Tuberculosis and Inhibits Apoptosis of Monocytes by Targeting FOXO1

Macrophage apoptosis is a host innate defense mechanism against tuberculosis (TB). In this study, we found that percentage of apoptotic cells in peripheral blood monocytes from patients with active TB was lower than that from healthy controls (p<0.001). To understand whether microRNAs can modulat...

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Detalles Bibliográficos
Autores principales: Liu, Yanhua, Jiang, Jing, Wang, Xinjing, Zhai, Fei, Cheng, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813442/
https://www.ncbi.nlm.nih.gov/pubmed/24205217
http://dx.doi.org/10.1371/journal.pone.0078381