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Proliferation of Colorectal Cancer Is Promoted by Two Signaling Transduction Expression Patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK

One of the recent breakthroughs in cancer research is the identification of activating mutations in various receptor tyrosine kinase(RTK) pathways in many cancers including colorectal cancer(CRC). We hypothesize that, alternative to mutations, overexpression of various oncogenic RTKs may also underp...

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Detalles Bibliográficos
Autores principales: Yao, Yong-Liang, Shao, Jie, Zhang, Chunfu, Wu, Jian-Hong, Zhang, Qing-Hui, Wang, Jian-Jun, Zhu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813539/
https://www.ncbi.nlm.nih.gov/pubmed/24205104
http://dx.doi.org/10.1371/journal.pone.0078086