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CanDrA: Cancer-Specific Driver Missense Mutation Annotation with Optimized Features

Driver mutations are somatic mutations that provide growth advantage to tumor cells, while passenger mutations are those not functionally related to oncogenesis. Distinguishing drivers from passengers is challenging because drivers occur much less frequently than passengers, they tend to have low pr...

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Detalles Bibliográficos
Autores principales: Mao, Yong, Chen, Han, Liang, Han, Meric-Bernstam, Funda, Mills, Gordon B., Chen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813554/
https://www.ncbi.nlm.nih.gov/pubmed/24205039
http://dx.doi.org/10.1371/journal.pone.0077945