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CanDrA: Cancer-Specific Driver Missense Mutation Annotation with Optimized Features
Driver mutations are somatic mutations that provide growth advantage to tumor cells, while passenger mutations are those not functionally related to oncogenesis. Distinguishing drivers from passengers is challenging because drivers occur much less frequently than passengers, they tend to have low pr...
Autores principales: | Mao, Yong, Chen, Han, Liang, Han, Meric-Bernstam, Funda, Mills, Gordon B., Chen, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813554/ https://www.ncbi.nlm.nih.gov/pubmed/24205039 http://dx.doi.org/10.1371/journal.pone.0077945 |
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