Inferring Polymorphism-Induced Regulatory Gene Networks Active in Human Lymphocyte Cell Lines by Weighted Linear Mixed Model Analysis of Multiple RNA-Seq Datasets

Single-nucleotide polymorphisms (SNPs) contribute to the between-individual expression variation of many genes. A regulatory (trait-associated) SNP is usually located near or within a (host) gene, possibly influencing the gene’s transcription or/and post-transcriptional modification. But its targets...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K., Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813575/
https://www.ncbi.nlm.nih.gov/pubmed/24205334
http://dx.doi.org/10.1371/journal.pone.0078868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813575/
https://www.ncbi.nlm.nih.gov/pubmed/24205334
http://dx.doi.org/10.1371/journal.pone.0078868

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