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Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI(−/−) Mice
Interleukin-1 (IL-1) is a key pro-inflammatory cytokine, produced predominantly by peripheral immune cells but also by glia and some neuronal populations within the brain. Its signalling is mediated via the binding of IL-1α or IL-1β to the interleukin-1 type one receptor (IL-1RI). IL-1 plays a key r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813582/ https://www.ncbi.nlm.nih.gov/pubmed/24205219 http://dx.doi.org/10.1371/journal.pone.0078385 |