A Quantitative Assessment of Costimulation and Phosphatase Activity on Microclusters in Early T Cell Signaling

T cell signaling is triggered through stimulation of the T cell receptor and costimulatory receptors. Receptor activation leads to the formation of membrane-proximal protein microclusters. These clusters undergo tyrosine phosphorylation and organize multiprotein complexes thereby acting as molecular...

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Detalles Bibliográficos
Autores principales: Witsenburg, J. Joris, Glauner, Heike, Müller, Jörg P., Groenewoud, Johannes M. M., Roth, Günter, Böhmer, Frank-Dietmar, Adjobo-Hermans, Merel J. W., Brock, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813591/
https://www.ncbi.nlm.nih.gov/pubmed/24205378
http://dx.doi.org/10.1371/journal.pone.0079277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813591/
https://www.ncbi.nlm.nih.gov/pubmed/24205378
http://dx.doi.org/10.1371/journal.pone.0079277

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