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A Quantitative Assessment of Costimulation and Phosphatase Activity on Microclusters in Early T Cell Signaling
T cell signaling is triggered through stimulation of the T cell receptor and costimulatory receptors. Receptor activation leads to the formation of membrane-proximal protein microclusters. These clusters undergo tyrosine phosphorylation and organize multiprotein complexes thereby acting as molecular...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813591/ https://www.ncbi.nlm.nih.gov/pubmed/24205378 http://dx.doi.org/10.1371/journal.pone.0079277 |