The Absence of CCR7 Results in Dysregulated Monocyte Migration and Immunosuppression Facilitating Chronic Cutaneous Leishmaniasis

The protozoan parasite Leishmania major causes cutaneous lesions to develop at the site of infection, which are resolved with a strong Th1 immune response in resistant hosts, such as C57BL/6 mice. In contrast, the lesions ulcerate in susceptible hosts which display a Th2 response, such as BALB/c mic...

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Detalles Bibliográficos
Autores principales: Kling, Jessica C., Mack, Matthias, Körner, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813618/
https://www.ncbi.nlm.nih.gov/pubmed/24205367
http://dx.doi.org/10.1371/journal.pone.0079098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813618/
https://www.ncbi.nlm.nih.gov/pubmed/24205367
http://dx.doi.org/10.1371/journal.pone.0079098

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