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Prosapogenin A induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis

Signal transducer and activator of transcription 3 (STAT3) is considered to be an oncogene. Blocking STAT3 signaling may induce growth arrest and apoptosis in different types of tumors. Cancer cells utilize the glycolytic pathway to maintain cell growth even when adequate oxygen is present. Glycolys...

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Detalles Bibliográficos
Autores principales: WANG, TIAN-XIAO, ZHANG, ZHONG-QING, CONG, YUE, SHI, XIAO-YAN, LIU, YING-HUA, ZHAO, FANG-LI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813670/
https://www.ncbi.nlm.nih.gov/pubmed/24179517
http://dx.doi.org/10.3892/ol.2013.1561