Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome

Down Syndrome (DS) is a highly prevalent developmental disorder, affecting 1/700 births. Intellectual disability, which affects learning and memory, is present in all cases and is reflected by below average IQ. We sought to determine whether defective morphology and connectivity in neurons of the ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Haas, Matilda A., Bell, Donald, Slender, Amy, Lana-Elola, Eva, Watson-Scales, Sheona, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Guillemot, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813676/
https://www.ncbi.nlm.nih.gov/pubmed/24205261
http://dx.doi.org/10.1371/journal.pone.0078561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813676/
https://www.ncbi.nlm.nih.gov/pubmed/24205261
http://dx.doi.org/10.1371/journal.pone.0078561

Ejemplares similares