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The Effect of UGT1A1 Promoter Polymorphism in the Development of Hyperbilirubinemia and Cholelithiasis in Hemoglobinopathy Patients

Present study was aimed to explore the effect of (TA)(n) UGT1A1 gene promoter polymorphism on bilirubin metabolism, bilirubinaemia, predisposition to cholelithiasis and subsequent cholecystectomy, in Sickle-Cell Anemia (SCA) and beta-Thalasemia major (bTH) in Kuwaiti subjects compared to other popul...

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Detalles Bibliográficos
Autores principales: AlFadhli, Suad, Al-Jafer, Hassan, Hadi, Mays, Al-Mutairi, Mashael, Nizam, Rasheeba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813713/
https://www.ncbi.nlm.nih.gov/pubmed/24204915
http://dx.doi.org/10.1371/journal.pone.0077681