A Polyamine-Deficient Diet Prevents Oxaliplatin-Induced Acute Cold and Mechanical Hypersensitivity in Rats

BACKGROUND: Oxaliplatin is an anticancer drug used for the treatment of advanced colorectal cancer, but it can also cause painful peripheral neuropathies. The pathophysiology of these neuropathies has not been yet fully elucidated, but may involve spinal N-methyl-D-aspartate (NMDA) receptors, partic...

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Detalles Bibliográficos
Autores principales: Ferrier, Jérémy, Bayet-Robert, Mathilde, Pereira, Bruno, Daulhac, Laurence, Eschalier, Alain, Pezet, Denis, Moulinoux, Jacques-Philippe, Balayssac, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813736/
https://www.ncbi.nlm.nih.gov/pubmed/24204988
http://dx.doi.org/10.1371/journal.pone.0077828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813736/
https://www.ncbi.nlm.nih.gov/pubmed/24204988
http://dx.doi.org/10.1371/journal.pone.0077828

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