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Dissociable Effects of 5-HT2C Receptor Antagonism and Genetic Inactivation on Perseverance and Learned Non-Reward in an Egocentric Spatial Reversal Task

Cognitive flexibility can be assessed in reversal learning tests, which are sensitive to modulation of 5-HT(2C) receptor (5-HT(2C)R) function. Successful performance in these tests depends on at least two dissociable cognitive mechanisms which may separately dissipate associations of previous positi...

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Detalles Bibliográficos
Autores principales: Nilsson, Simon R. O., Somerville, Elizabeth M., Clifton, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813744/
https://www.ncbi.nlm.nih.gov/pubmed/24204954
http://dx.doi.org/10.1371/journal.pone.0077762