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Dissociable Effects of 5-HT2C Receptor Antagonism and Genetic Inactivation on Perseverance and Learned Non-Reward in an Egocentric Spatial Reversal Task
Cognitive flexibility can be assessed in reversal learning tests, which are sensitive to modulation of 5-HT(2C) receptor (5-HT(2C)R) function. Successful performance in these tests depends on at least two dissociable cognitive mechanisms which may separately dissipate associations of previous positi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813744/ https://www.ncbi.nlm.nih.gov/pubmed/24204954 http://dx.doi.org/10.1371/journal.pone.0077762 |