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The Natural Product Magnolol as a Lead Structure for the Development of Potent Cannabinoid Receptor Agonists
Magnolol (4-allyl-2-(5-allyl-2-hydroxyphenyl)phenol), the main bioactive constituent of the medicinal plant Magnolia officinalis, and its main metabolite tetrahydromagnolol were recently found to activate cannabinoid (CB) receptors. We now investigated the structure-activity relationships of (tetrah...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813752/ https://www.ncbi.nlm.nih.gov/pubmed/24204944 http://dx.doi.org/10.1371/journal.pone.0077739 |