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The Vitamin D Receptor Agonist BXL-01-0029 as a Potential New Pharmacological Tool for the Treatment of Inflammatory Myopathies

OBJECTIVE: This study aims to investigate in vitro the effect of the VDR agonist BXL-01-0029 onto IFNγ/TNFα-induced CXCL10 secretion by human skeletal muscle cells compared to elocalcitol (VDR agonist), methylprednisolone, methotrexate, cyclosporin A, infliximab and leflunomide; to assess in vivo ci...

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Detalles Bibliográficos
Autores principales: Di Luigi, Luigi, Sottili, Mariangela, Antinozzi, Cristina, Vannelli, Gabriella Barbara, Romanelli, Francesco, Riccieri, Valeria, Valesini, Guido, Lenzi, Andrea, Crescioli, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813757/
https://www.ncbi.nlm.nih.gov/pubmed/24204948
http://dx.doi.org/10.1371/journal.pone.0077745