Extension of Life Span by Impaired Glucose Metabolism in Caenorhabditis elegans Is Accompanied by Structural Rearrangements of the Transcriptomic Network

Glucose restriction mimicked by feeding the roundworm Caenorhabditis elegans with 2-deoxy-D-glucose (DOG) - a glucose molecule that lacks the ability to undergo glycolysis - has been found to increase the life span of the nematodes considerably. To facilitate understanding of the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Priebe, Steffen, Menzel, Uwe, Zarse, Kim, Groth, Marco, Platzer, Matthias, Ristow, Michael, Guthke, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813781/
https://www.ncbi.nlm.nih.gov/pubmed/24204961
http://dx.doi.org/10.1371/journal.pone.0077776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813781/
https://www.ncbi.nlm.nih.gov/pubmed/24204961
http://dx.doi.org/10.1371/journal.pone.0077776

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