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Correlation of MLH1 and MGMT methylation levels between peripheral blood leukocytes and colorectal tissue DNA samples in colorectal cancer patients

CpG island methylation in the promoter regions of the DNA mismatch repair gene mutator L homologue 1 (MLH1) and DNA repair gene O(6)-methylguanine-DNA methyltransferase (MGMT) genes has been shown to occur in the leukocytes of peripheral blood and colorectal tissue. However, it is unclear whether th...

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Detalles Bibliográficos
Autores principales: LI, XIA, WANG, YIBAINA, ZHANG, ZUOMING, YAO, XIAOPING, GE, JIE, ZHAO, YASHUANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813787/
https://www.ncbi.nlm.nih.gov/pubmed/24179526
http://dx.doi.org/10.3892/ol.2013.1543