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Inhibitory effect of valproic acid on bladder cancer in combination with chemotherapeutic agents in vitro and in vivo

Histone deacetylase inhibitors (HDACIs) are a promising class of drugs that act as antiproliferative agents by promoting differentiation and inducing apoptosis. Valproic acid (VPA) is an HDACI that has been widely used as an anti-convulsant and shows promise as a chemotherapeutic drug for a number o...

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Detalles Bibliográficos
Autores principales: WANG, DEGUI, JING, YUHONG, OUYANG, SIWEI, LIU, BEI, ZHU, TIANYUAN, NIU, HAITAO, TIAN, YINGXIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813788/
https://www.ncbi.nlm.nih.gov/pubmed/24179547
http://dx.doi.org/10.3892/ol.2013.1565