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Pro-apoptotic and migration-suppressing potential of EGCG, and the involvement of AMPK in the p53-mediated modulation of VEGF and MMP-9 expression

The present study investigated the regulatory mechanisms by which epigallocatechin-3-gallate (EGCG) exerts vascular endothelial growth factor (VEGF)-, p53- and AMP-activated protein kinase (AMPK)-associated pro-apoptotic and migration-suppressing effects on colon cancer cells. EGCG decreased the exp...

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Detalles Bibliográficos
Autores principales: PARK, SONG YI, JUNG, CHANG HEE, SONG, BOKYUNG, PARK, OCK JIN, KIM, YOUNG-MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813811/
https://www.ncbi.nlm.nih.gov/pubmed/24179522
http://dx.doi.org/10.3892/ol.2013.1533