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Microsatellite instability and loss of heterozygosity detected in middle-aged patients with sporadic colon cancer: A retrospective study

Microsatellite instability (MSI) is a mutator phenotype that results from a defective mismatch repair (MMR) pathway. The present study examined the incidence of MSI and loss of heterozygosity (LOH) according to five markers from the panel of the National Cancer Institute (NCI) in 38 colorectal cance...

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Detalles Bibliográficos
Autores principales: KAMAT, NASIR, KHIDHIR, MOHAMMED A., ALASHARI, MOUIED M., RANNUG, ULF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813818/
https://www.ncbi.nlm.nih.gov/pubmed/24179534
http://dx.doi.org/10.3892/ol.2013.1573