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Population Growth Inflates the Per-Individual Number of Deleterious Mutations and Reduces Their Mean Effect
This study addresses the question of how purifying selection operates during recent rapid population growth such as has been experienced by human populations. This is not a straightforward problem because the human population is not at equilibrium: population genetics predicts that, on the one hand,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813877/ https://www.ncbi.nlm.nih.gov/pubmed/23979573 http://dx.doi.org/10.1534/genetics.113.153973 |