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Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2

The effect of electrical stimulation on neuronal membrane potential is frequency dependent. Low frequency electrical stimulation can evoke action potentials, whereas high frequency stimulation can inhibit action potential transmission. Optical stimulation of channelrhodopsin-2 (ChR2) expressed in ne...

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Detalles Bibliográficos
Autores principales: Liske, Holly, Qian, Xiang, Anikeeva, Polina, Deisseroth, Karl, Delp, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813941/
https://www.ncbi.nlm.nih.gov/pubmed/24173561
http://dx.doi.org/10.1038/srep03110