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How Changes in Affinity of Corticosteroid-binding Globulin Modulate Free Cortisol Concentration

CONTEXT: Recent studies of corticosteroid-binding globulin (CBG) indicate that it does not merely transport cortisol passively but also actively regulates its release in the circulation. We show how CBG binding affinity can vary to give changes in free cortisol concentration in a physiologically rel...

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Detalles Bibliográficos
Autores principales: Chan, Wee Lee, Carrell, Robin W., Zhou, Aiwu, Read, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813945/
https://www.ncbi.nlm.nih.gov/pubmed/23783094
http://dx.doi.org/10.1210/jc.2012-4280