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Altered methylation and expression of ER-associated degradation factors in long-term alcohol and constitutive ER stress-induced murine hepatic tumors

Mortality from liver cancer in humans is increasingly attributable to heavy or long-term alcohol consumption. The mechanisms by which alcohol exerts its carcinogenic effect are not well understood. In this study, the role of alcohol-induced endoplasmic reticulum (ER) stress response in liver cancer...

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Detalles Bibliográficos
Autores principales: Han, Hui, Hu, Jay, Lau, Mo Y., Feng, Min, Petrovic, Lydia M., Ji, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813967/
https://www.ncbi.nlm.nih.gov/pubmed/24198826
http://dx.doi.org/10.3389/fgene.2013.00224