Subdued, a TMEM16 family Ca(2+)-activated Cl(−) channel in Drosophila melanogaster with an unexpected role in host defense

TMEM16A and TMEM16B are calcium-activated chloride channels (CaCCs) with important functions in mammalian physiology. Whether distant relatives of the vertebrate TMEM16 families also form CaCCs is an intriguing open question. Here we report that a TMEM16 family member from Drosophila melanogaster, S...

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Detalles Bibliográficos
Autores principales: Wong, Xiu Ming, Younger, Susan, Peters, Christian J, Jan, Yuh Nung, Jan, Lily Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814000/
https://www.ncbi.nlm.nih.gov/pubmed/24192034
http://dx.doi.org/10.7554/eLife.00862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814000/
https://www.ncbi.nlm.nih.gov/pubmed/24192034
http://dx.doi.org/10.7554/eLife.00862

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