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Subdued, a TMEM16 family Ca(2+)-activated Cl(−) channel in Drosophila melanogaster with an unexpected role in host defense
TMEM16A and TMEM16B are calcium-activated chloride channels (CaCCs) with important functions in mammalian physiology. Whether distant relatives of the vertebrate TMEM16 families also form CaCCs is an intriguing open question. Here we report that a TMEM16 family member from Drosophila melanogaster, S...
Autores principales: | Wong, Xiu Ming, Younger, Susan, Peters, Christian J, Jan, Yuh Nung, Jan, Lily Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814000/ https://www.ncbi.nlm.nih.gov/pubmed/24192034 http://dx.doi.org/10.7554/eLife.00862 |
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