Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation

Anchoring proteins sequester kinases with their substrates to locally disseminate intracellular signals and avert indiscriminate transmission of these responses throughout the cell. Mechanistic understanding of this process is hampered by limited structural information on these macromolecular comple...

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Detalles Bibliográficos
Autores principales: Smith, F Donelson, Reichow, Steve L, Esseltine, Jessica L, Shi, Dan, Langeberg, Lorene K, Scott, John D, Gonen, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814001/
https://www.ncbi.nlm.nih.gov/pubmed/24192038
http://dx.doi.org/10.7554/eLife.01319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814001/
https://www.ncbi.nlm.nih.gov/pubmed/24192038
http://dx.doi.org/10.7554/eLife.01319

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