Oligomerization and Ca(2+)/calmodulin control binding of the ER Ca(2+)-sensors STIM1 and STIM2 to plasma membrane lipids

Ca(2+) (calcium) homoeostasis and signalling rely on physical contacts between Ca(2+) sensors in the ER (endoplasmic reticulum) and Ca(2+) channels in the PM (plasma membrane). STIM1 (stromal interaction molecule 1) and STIM2 Ca(2+) sensors oligomerize upon Ca(2+) depletion in the ER lumen, contact...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Rajesh, Müller, Hans-Michael, Nickel, Walter, Seedorf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814058/
https://www.ncbi.nlm.nih.gov/pubmed/24044355
http://dx.doi.org/10.1042/BSR20130089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814058/
https://www.ncbi.nlm.nih.gov/pubmed/24044355
http://dx.doi.org/10.1042/BSR20130089

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