Local Gene Transfer of OPG Prevents Joint Damage and Disease Progression in Collagen-Induced Arthritis

This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model. A single periarticular injection of AAV-OPG or AAV-LacZ on the arthritic paw successfully incorporated the exogenous gene to the local tissue and resulted in marked transgene expres...

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Detalles Bibliográficos
Autores principales: Zhang, Qingguo, Gong, Weiming, Ning, Bin, Nie, Lin, Wooley, Paul H., Yang, Shang-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814078/
https://www.ncbi.nlm.nih.gov/pubmed/24222748
http://dx.doi.org/10.1155/2013/718061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814078/
https://www.ncbi.nlm.nih.gov/pubmed/24222748
http://dx.doi.org/10.1155/2013/718061

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