Endosomal acidification by Na(+)/H(+) exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling

To facilitate polarized vesicular trafficking and signal transduction, neuronal endosomes have evolved sophisticated mechanisms for pH homeostasis. NHE5 is a member of the Na(+)/H(+) exchanger family and is abundantly expressed in neurons and associates with recycling endosomes. Here we show that NH...

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Detalles Bibliográficos
Autores principales: Diering, Graham H., Numata, Yuka, Fan, Steven, Church, John, Numata, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814139/
https://www.ncbi.nlm.nih.gov/pubmed/24006492
http://dx.doi.org/10.1091/mbc.E12-06-0445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814139/
https://www.ncbi.nlm.nih.gov/pubmed/24006492
http://dx.doi.org/10.1091/mbc.E12-06-0445

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