Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition

Induction of epithelial–myofibroblast transition (EMyT), a robust fibrogenic phenotype change hallmarked by α-smooth muscle actin (SMA) expression, requires transforming growth factor-β1 (TGFβ) and the absence/uncoupling of intracellular contacts. This suggests that an “injured” epithelium may be to...

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Detalles Bibliográficos
Autores principales: Speight, Pam, Nakano, Hiroyasu, Kelley, Thomas J., Hinz, Boris, Kapus, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814143/
https://www.ncbi.nlm.nih.gov/pubmed/24006486
http://dx.doi.org/10.1091/mbc.E13-04-0220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814143/
https://www.ncbi.nlm.nih.gov/pubmed/24006486
http://dx.doi.org/10.1091/mbc.E13-04-0220

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