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Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton

Chemotaxis allows neutrophils to seek out sites of infection and inflammation. The asymmetric accumulation of filamentous actin (F-actin) at the leading edge provides the driving force for protrusion and is essential for the development and maintenance of neutrophil polarity. The mechanism that gove...

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Detalles Bibliográficos
Autores principales: He, Yuan, Li, Dong, Cook, Sara L., Yoon, Mee-Sup, Kapoor, Ashish, Rao, Christopher V., Kenis, Paul J. A., Chen, Jie, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814157/
https://www.ncbi.nlm.nih.gov/pubmed/24006489
http://dx.doi.org/10.1091/mbc.E13-07-0405