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Robust and specific ratiometric biosensing using a copper-free clicked quantum dot–DNA aptamer sensor

We report herein the successful preparation of a compact and functional CdSe–ZnS core–shell quantum dot (QD)–DNA conjugate via highly efficient copper-free “click chemistry” (CFCC) between a dihydro-lipoic acid–polyethylene glycol–azide (DHLA–PEG–N(3)) capped QD and a cyclooctyne modified DNA. This...

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Detalles Bibliográficos
Autores principales: Zhang, Haiyan, Feng, Guoqiang, Guo, Yuan, Zhou, Dejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814187/
https://www.ncbi.nlm.nih.gov/pubmed/24056667
http://dx.doi.org/10.1039/c3nr02897f