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Female and Male Gamete Mitochondria Are Distinct and Complementary in Transcription, Structure, and Genome Function

Respiratory electron transport in mitochondria is coupled to ATP synthesis while generating mutagenic oxygen free radicals. Mitochondrial DNA mutation then accumulates with age, and may set a limit to the lifespan of individual, multicellular organisms. Why is this mutation not inherited? Here we de...

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Detalles Bibliográficos
Autores principales: de Paula, Wilson B.M., Agip, Ahmed-Noor A., Missirlis, Fanis, Ashworth, Rachel, Vizcay-Barrena, Gema, Lucas, Cathy H., Allen, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814205/
https://www.ncbi.nlm.nih.gov/pubmed/24068653
http://dx.doi.org/10.1093/gbe/evt147