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Biochemical fluctuations, optimisation and the linear noise approximation

BACKGROUND: Stochastic fluctuations in molecular numbers have been in many cases shown to be crucial for the understanding of biochemical systems. However, the systematic study of these fluctuations is severely hindered by the high computational demand of stochastic simulation algorithms. This is pa...

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Detalles Bibliográficos
Autores principales: Pahle, Jürgen, Challenger, Joseph D, Mendes, Pedro, McKane, Alan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814289/
https://www.ncbi.nlm.nih.gov/pubmed/22805626
http://dx.doi.org/10.1186/1752-0509-6-86