Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

It is common practice in genome-wide association studies (GWAS) to focus on the relationship between disease risk and genetic variants one marker at a time. When relevant genes are identified it is often possible to implicate biological intermediates and pathways likely to be involved in disease aet...

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Detalles Bibliográficos
Autores principales: Evans, David M., Brion, Marie Jo A., Paternoster, Lavinia, Kemp, John P., McMahon, George, Munafò, Marcus, Whitfield, John B., Medland, Sarah E., Montgomery, Grant W., Timpson, Nicholas J., St. Pourcain, Beate, Lawlor, Debbie A., Martin, Nicholas G., Dehghan, Abbas, Hirschhorn, Joel, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814299/
https://www.ncbi.nlm.nih.gov/pubmed/24204319
http://dx.doi.org/10.1371/journal.pgen.1003919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814299/
https://www.ncbi.nlm.nih.gov/pubmed/24204319
http://dx.doi.org/10.1371/journal.pgen.1003919

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