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Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

Interactions between HLA class I molecules and killer-cell immunoglobulin-like receptors (KIR) control natural killer cell (NK) functions in immunity and reproduction. Encoded by genes on different chromosomes, these polymorphic ligands and receptors correlate highly with disease resistance and susc...

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Detalles Bibliográficos
Autores principales: Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Hilton, Hugo G., Pando, Marcelo J., Koram, Kwadwo A., Riley, Eleanor M., Abi-Rached, Laurent, Parham, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814319/
https://www.ncbi.nlm.nih.gov/pubmed/24204327
http://dx.doi.org/10.1371/journal.pgen.1003938