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Tracking Proliferative History in Lymphocyte Development with Cre-Mediated Sister Chromatid Recombination

Tracking and isolating live cells based on their proliferative history in live animals remains a technical challenge in animal studies. We have designed a genetic marking system for tracking the proliferative frequency and history of lymphocytes during their development and homeostatic maintenance....

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Detalles Bibliográficos
Autores principales: Zhang, Baojun, Dai, Meifang, Li, Qi-Jing, Zhuang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814321/
https://www.ncbi.nlm.nih.gov/pubmed/24204301
http://dx.doi.org/10.1371/journal.pgen.1003887