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Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication

Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the host cell cytoplasm where the viral genome replicates and virions assemble. The membranous web is thought to concentrate viral components and hide viral RNA from pattern recognition receptors. We have uncovered...

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Detalles Bibliográficos
Autores principales: Neufeldt, Christopher J., Joyce, Michael A., Levin, Aviad, Steenbergen, Rineke H., Pang, Daniel, Shields, Justin, Tyrrell, D. Lorne J., Wozniak, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814334/
https://www.ncbi.nlm.nih.gov/pubmed/24204278
http://dx.doi.org/10.1371/journal.ppat.1003744