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Robust gene silencing mediated by antisense small RNAs in the pathogenic protist Entamoeba histolytica

RNA interference uses small RNAs (sRNA), which target genes for sequence-specific silencing. The parasite Entamoeba histolytica contains an abundant repertoire of 27 nt antisense (AS) sRNA with 5′-polyphosphate termini, but their roles in regulating gene expression have not been well established. We...

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Detalles Bibliográficos
Autores principales: Morf, Laura, Pearson, Richard J., Wang, Angelia S., Singh, Upinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814356/
https://www.ncbi.nlm.nih.gov/pubmed/23935116
http://dx.doi.org/10.1093/nar/gkt717