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Purification of a specific native genomic locus for proteomic analysis

Here, we describe an approach to isolate native chromatin sections without genomic engineering for label-free proteomic identification of associated proteins and histone post-translational modifications. A transcription activator-like (TAL) protein A fusion protein was designed to recognize a unique...

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Detalles Bibliográficos
Autores principales: Byrum, Stephanie D., Taverna, Sean D., Tackett, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814360/
https://www.ncbi.nlm.nih.gov/pubmed/24030711
http://dx.doi.org/10.1093/nar/gkt822