G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

The formation of a single G-quadruplex structure adopted by a promising 25 nt G-rich vascular endothelial growth factor aptamer in a K(+) rich environment was facilitated by locked nucleic acid modifications. An unprecedented all parallel-stranded monomeric G-quadruplex with three G-quartet planes e...

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Detalles Bibliográficos
Autores principales: Marušič, Maja, Veedu, Rakesh N., Wengel, Jesper, Plavec, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814366/
https://www.ncbi.nlm.nih.gov/pubmed/23935071
http://dx.doi.org/10.1093/nar/gkt697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814366/
https://www.ncbi.nlm.nih.gov/pubmed/23935071
http://dx.doi.org/10.1093/nar/gkt697

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