Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex

Transcription elongation consists of repetition of the nucleotide addition cycle: phosphodiester bond formation, translocation and binding of the next nucleotide. Inhibitor of multi-subunit RNA polymerase tagetitoxin (TGT) enigmatically slows down addition of nucleotides in a sequence-dependent mann...

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Detalles Bibliográficos
Autores principales: Yuzenkova, Yulia, Roghanian, Mohammad, Bochkareva, Aleksandra, Zenkin, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814378/
https://www.ncbi.nlm.nih.gov/pubmed/23935117
http://dx.doi.org/10.1093/nar/gkt708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814378/
https://www.ncbi.nlm.nih.gov/pubmed/23935117
http://dx.doi.org/10.1093/nar/gkt708

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