Cargando…

Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex

Transcription elongation consists of repetition of the nucleotide addition cycle: phosphodiester bond formation, translocation and binding of the next nucleotide. Inhibitor of multi-subunit RNA polymerase tagetitoxin (TGT) enigmatically slows down addition of nucleotides in a sequence-dependent mann...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuzenkova, Yulia, Roghanian, Mohammad, Bochkareva, Aleksandra, Zenkin, Nikolay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814378/ https://www.ncbi.nlm.nih.gov/pubmed/23935117 http://dx.doi.org/10.1093/nar/gkt708

Ejemplares similares

Bacterial global regulators DksA/ppGpp increase fidelity of transcription
por: Roghanian, Mohammad, et al.
Publicado: (2015)

Bacteriophage Xp10 anti-termination factor p7 induces forward translocation by host RNA polymerase
por: Zenkin, Nikolay, et al.
Publicado: (2015)

Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae
por: Yuzenkova, Yulia, et al.
Publicado: (2014)

Ribonucleoprotein particles of bacterial small non-coding RNA IsrA (IS61 or McaS) and its interaction with RNA polymerase core may link transcription to mRNA fate
por: van Nues, Rob W., et al.
Publicado: (2016)

Misincorporation by RNA polymerase is a major source of transcription pausing in vivo
por: James, Katherine, et al.
Publicado: (2017)

Bacterial RNA polymerase caps RNA with various cofactors and cell wall precursors
por: Julius, Christina, et al.
Publicado: (2017)

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex
por: Gopalan, Sneha, et al.
Publicado: (2018)

TEFM is a potent stimulator of mitochondrial transcription elongation in vitro
por: Posse, Viktor, et al.
Publicado: (2015)

Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis
por: Kindgren, Peter, et al.
Publicado: (2020)

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation
por: Gómez-Herreros, Fernando, et al.
Publicado: (2017)

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation
por: Bottardi, Stefania, et al.
Publicado: (2011)

Different elongation factors distinctly modulate RNA polymerase II transcription in Arabidopsis
por: Obermeyer, Simon, et al.
Publicado: (2023)

Transcription initiation factor DksA has diverse effects on RNA chain elongation
por: Furman, Ran, et al.
Publicado: (2012)

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription
por: Lu, Huasong, et al.
Publicado: (2015)

The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome
por: Crickard, John B., et al.
Publicado: (2017)

The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4
por: Begley, Victoria, et al.
Publicado: (2019)

A pre-initiation complex at the 3′-end of genes drives antisense transcription independent of divergent sense transcription
por: Murray, Struan C., et al.
Publicado: (2012)

A polar barrier to transcription can be circumvented by remodeler-induced nucleosome translocation
por: Gaykalova, Daria A., et al.
Publicado: (2011)

The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation
por: Stefanovsky, Victor Y., et al.
Publicado: (2008)

The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis
por: Dürr, Julius, et al.
Publicado: (2014)

The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae
por: Reim, Natalia I, et al.
Publicado: (2020)

CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
por: Tellier, Michael, et al.
Publicado: (2020)

Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p
por: Wong, Chi-Ming, et al.
Publicado: (2010)

Stepwise mechanism for transcription fidelity
por: Yuzenkova, Yulia, et al.
Publicado: (2010)

Transcription elongator SPT6L regulates the occupancies of the SWI2/SNF2 chromatin remodelers SYD/BRM and nucleosomes at transcription start sites in Arabidopsis
por: Shu, Jie, et al.
Publicado: (2022)

Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling
por: Lee, Bomi, et al.
Publicado: (2016)

TFIIH is an elongation factor of RNA polymerase I
por: Assfalg, Robin, et al.
Publicado: (2012)

RNA polymerase-promoter interactions determining different stability of the Escherichia coli and Thermus aquaticus transcription initiation complexes
por: Mekler, Vladimir, et al.
Publicado: (2012)

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations
por: Nomidis, Stefanos K, et al.
Publicado: (2022)

Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures
por: Xu, Jun, et al.
Publicado: (2021)

A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation
por: Dronamraju, Raghuvar, et al.
Publicado: (2014)

Directional transition from initiation to elongation in bacterial translation
por: Goyal, Akanksha, et al.
Publicado: (2015)

H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells
por: He, Runsheng, et al.
Publicado: (2017)

Specification of the NF-κB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKKε
por: Moreno, Rita, et al.
Publicado: (2010)

CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2
por: Seo, Woo-Young, et al.
Publicado: (2013)

Heterochromatin protein 1 gamma and IκB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages
por: Thorne, James L., et al.
Publicado: (2012)

Sas3 and Ada2(Gcn5)-dependent histone H3 acetylation is required for transcription elongation at the de-repressed FLO1 gene
por: Church, Michael, et al.
Publicado: (2017)

Elongation factor TFIIS is essential for heat stress adaptation in plants
por: Szádeczky-Kardoss, István, et al.
Publicado: (2022)

Regulatory consequences of gene translocation in bacteria
por: Block, Dena H. S., et al.
Publicado: (2012)

The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium
por: Chan, Ngai Ting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4jodjraso9mm045ebe8denl1j4